FYI:
The latest version of Foobar 1.0.1 now support the Mykerinos board.
With the previous version, Foobar was crashing during the Asio driver starting process and report an error about -being unable to support a multichannel board-.
Now the Mykerinos VS3 Mixer appears and could be configured but the drivers stop every time when you click on next.
The workaround is to use the scroll bar (when you hit the end the track will change).

I was able to interface the Mykerinos Audio PCI Card with a free software called CUE 1.7 (http://www.gasteropod.ch/)
With CUE 1.7 I was able to playback stereo lossless flac files trough the Mykerinos.
The ADAT output of the Mykerinos is connected to a Merging DUA II converter. (@ 44.1Khz)
The DUA II is referenced on ODI, and the Mykerinos run on INT sync.

The Mykerinos almost work with Foobar,
the VS3 application start during the configuration but Foobar report an error message about not supporting multitrack cards.

Using Pyramix will allow DSD playback but the essential audio processing occur on the card itself, so other software may be used for playback at lower resolution.

The Mykerinos card is an excellent audio product introduced in 1998,
one of the first audio card on the market to support MADI I/O and also one of the best card to be referenced with Video Black-Burst and Tri-Level Sync.

It's amazing to observe that this card is based on chip usually used for TV Box. (the TriMedia Chip).

I got no doubt that the Mykerinos card could be at the heart of a High End Media Server.